Most experts consider metformin to be the safest medication for type 2 diabetes because it has been used for many decades and is effective, affordable, and safe. The American Diabetes Association (ADA) recommends metformin as a first-line treatment for type 2 diabetes. All sulphonylureas have similar effects on blood glucose levels, but differ in terms of side effects, how often they are taken, and interactions with other medications. The most common side effects of sulphonylureas are hypoglycaemia and weight gain.
The drug also protects the heart and reduces the risks of heart disease and stroke. It also promotes weight loss and the reduction of HbA1c. It's an effective option for lowering HbA1c and blood sugar levels. In addition, it also helps with weight loss, which eventually leads to better sugar control.
There are many alternatives available for metformin with different health benefits. These alternatives are SGLT inhibitors (2), GLP receptor agonists (1), sulphonylureas (SFU), DPP inhibitors (4) and thiazolidinediones (TZDs). Metformin helps provide better blood sugar control by increasing insulin resistance in the body. If you have good blood sugar control, you can keep your sugar levels under control with a healthy diet for diabetics, exercise and lifestyle modifications.
To support these practices, you can choose herbal alternatives to metformin to reduce high sugar levels and HbA1c. Herbal alternatives include fenugreek, neem, bitter gourd, jamun, gurmar, and other herbs. Metformin is a reliable and affordable medication for the treatment of type 2 diabetes. However, it is a safe medication, but few people show any side effects. Common side effects of metformin are nausea, vomiting, stomach cramps, diarrhea, vitamin B12 deficiency, weight loss, nerve damage, hypoglycemia, risk of lactic acidosis, kidney damage, etc.
In addition, some people have drug interactions with their existing medications for other health conditions. This medication has been shown to reduce A1C levels by 0.7% to 1%, but most patients prefer it especially because of the significant weight loss it can cause. This is an invincible drug for type 2 diabetes, but some people need their alternative for several reasons. The dosage of diabetes medicines depends on each person's needs and sugar levels, so ask your doctor for the correct dose. For example, metformin and a DPP-4 inhibitor can be used together soon after you are diagnosed with type 2 diabetes to help keep blood glucose levels within normal levels.
Patients will also lose weight with this medication, although it can cause pain and swelling in the pancreas. The four drugs evaluated were added to treatment with metformin, which is the first-line drug for treating type 2 diabetes. There are different types or classes of medications that work in different ways to lower blood glucose levels (also known as blood sugar). People with diabetes who keep their blood glucose levels close to normal generally have a much lower risk of developing diabetes complications, such as nerve, kidney and eye diseases.
If you take metformin with another oral diabetes medication, there may be a pill that combines both medicines. Metformin is considered the first-line oral agent for patients with diabetes and can be used to treat prediabetes. It was designed to compare four major drugs approved by the FDA at the time GRADE began treating diabetes in combination with metformin. Bromocriptine (Cycloset) is a dopamine-2 agonist approved by the FDA to lower blood glucose levels in people with type 2 diabetes.
The NIH is the principal federal agency that conducts and supports basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures of common and rare diseases. Metformin is the first-line medication prescribed by any doctor or diabetologist for type 2 diabetes. GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes.